Summary. Fluoxetine (Prozac, Sarafem, Prozac Weekly) is a drug prescribed for the treatemnt of depression, bulimia, obsessive-compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder (PMDD). The Zoloft dosage that doctors usually recommend for adults with depression or obsessive-compulsive disorder is 50 mg once a day. Although the starting dose for people with panic disorder, post-traumatic stress disorder, or social anxiety disorder is typically 25 mg daily, healthcare providers often increase that dose to 50 mg daily. Learn about Prozac (Fluoxetine Hcl) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. For the treatment of depression or OCD, the recommended starting Prozac dosage is 20 mg once a day. This eMedTV segment also provides dosing guidelines for bulimia and panic disorder treatment and offers tips for those taking the antidepressant. Dosage in Patients with MDD, OCD, PD, PTSD, and SAD. The recommended initial dosage and maximum ZOLOFT dosage in patients with MDD, OCD, PD, PTSD, and SAD are displayed in Table 1 below. by Michael A. Jenike, M.D. Professor of Psychiatry Harvard Medical School Chairman, OC Foundation Scientific Advisory Board. Overview of OCD. Obsessive-Compulsive Disorder (OCD) is a potentially devastating illness that can result in considerable social and economic disability for both patients and their family members. Pediatric (children and adolescents) — Initiate PROZAC 10 or 20 mg/day. After 1 week at 10 mg/day, increase the dose to 20 mg/day. However, due to higher plasma levels in lower weight children, the starting and target dose in this group may be 10 mg/day. Prozac is the brand name of fluoxetine, a prescription drug used to treat depression. This antidepressant is in a class of drugs known as selective serotonin reuptake inhibitors, or SSRIs. • Serotonin Syndrome and MAOIs: Do not use MAOIs intended to treat psychiatric disorders with PROZAC or within 5 weeks of stopping treatment with PROZAC. Recommended dosage The recommended dosage of sertraline depends on the disorder being treated. The initial recommended dosage for depression and obsessive-compulsive disorder is 50 mg daily.